Scientists at Oregon Health & Science University (OHSU) have unveiled groundbreaking research that could pave the way for LGBTQIA+ couples to have biological children of their own.
The innovative technique, known as in vitro gametogenesis (IVG), involves the transformation of a skin cell into a viable egg.
In their study, OHSU researchers extracted a skin cell from a mouse, eliminated its nucleus, and then implanted it into a donor egg. They subsequently manipulated the nucleus to halve the chromosomes.
This chromosome reduction marks a significant departure from cloning, as it enables the presence of DNA from two donors, unlike cloning, which relies solely on DNA from one donor.
Following fertilization with sperm, a process akin to in vitro fertilization, the resulting diploid embryo boasts two sets of chromosomes, ensuring the offspring inherit an equal blend of genetics from both parents.
Dr. Shoukhrat Mitalipov, Director of the OHSU Center for Embryonic Cell and Gene Therapy, emphasized the potential of the technique: “The goal is to produce eggs for patients who don’t have their own eggs, including women of advanced maternal age or those rendered unable to produce viable eggs due to prior cancer treatment or other causes.”
Moreover, the research raises the prospect of genetic connection for children of same-sex male couples.
